Relation between neutralization of Epstein-Barr virus and antibodies to cell-membrane antigens-induced by the virus
Affiliations
- PMID: 18605425
Item in Clipboard
Relation between neutralization of Epstein-Barr virus and antibodies to cell-membrane antigens-induced by the virus
J Natl Cancer Inst.
1970 Nov.
Abstract
The neutralization of Epstein-Barr virus (EBV) infectivity by sera with known antibody activities against EBV-associated antigens was investigated in experimentally infected Raji and RPMI 64-10 cells. Antibodies against EBV-induced cell-membrane antigens were apparently responsible for neutralization of viral infectivity. Antibodies against EBV capsid antigens and EBV-induced early antigens were not involved. The implication of these results on the relationship of the membrane antigens to the infectious virus particle is discussed.
Similar articles
-
Restricted low-level human antibody responses against Epstein-Barr virus (EBV)-encoded latent membrane protein 1 in a subgroup of patients with EBV-associated diseases.J Infect Dis. 1999 May;179(5):1108-15. doi: 10.1086/314704. J Infect Dis. 1999. PMID: 10191211
-
Epstein-Barr virus infections.Can Med Assoc J. 1974 Jan 5;110(1):9-10. Can Med Assoc J. 1974. PMID: 4358535 Free PMC article. No abstract available.
-
Antibody patterns in different human sera against intracellular and membrane-antigen complexes associated with Epstein-Barr virus.J Natl Cancer Inst. 1970 Mar;44(3):595-610. J Natl Cancer Inst. 1970. PMID: 11515428 No abstract available.
-
Epstein-barr-virus nuclear antigen.Prog Med Virol. 1982;28:145-79. Prog Med Virol. 1982. PMID: 6283600 Review. No abstract available.
-
[Role of the Epstein-Barr virus in human pathology].Acta Haematol Pol. 1979 Jul-Sep;10(3):183-91. Acta Haematol Pol. 1979. PMID: 228518 Review. Polish. No abstract available.
Cited by
-
Primary immune responses by cord blood CD4(+) T cells and NK cells inhibit Epstein-Barr virus B-cell transformation in vitro.J Virol. 2002 May;76(10):5071-81. doi: 10.1128/jvi.76.10.5071-5081.2002. J Virol. 2002. PMID: 11967323 Free PMC article.
-
Control of viral disease: the development of Epstein-Barr virus vaccines.Springer Semin Immunopathol. 1991;13(2):249-62. doi: 10.1007/BF00201472. Springer Semin Immunopathol. 1991. PMID: 1664989 Review. No abstract available.
-
Soluble rhesus lymphocryptovirus gp350 protects against infection and reduces viral loads in animals that become infected with virus after challenge.PLoS Pathog. 2011 Oct;7(10):e1002308. doi: 10.1371/journal.ppat.1002308. Epub 2011 Oct 20. PLoS Pathog. 2011. PMID: 22028652 Free PMC article.
-
Human antibody titers to Epstein-Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay.Virology. 2009 Sep 1;391(2):249-56. doi: 10.1016/j.virol.2009.06.013. Epub 2009 Jul 7. Virology. 2009. PMID: 19584018 Free PMC article.
-
Immunological studies on Burkitt's lymphoma.Postgrad Med J. 1971 Mar;47(545):141-55. doi: 10.1136/pgmj.47.545.141. Postgrad Med J. 1971. PMID: 4932902 Free PMC article. Review. No abstract available.