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Comment
. 2008 Jul 8;18(13):R561-3.
doi: 10.1016/j.cub.2008.05.035.

RNA interference: endogenous siRNAs derived from transposable elements

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RNA interference: endogenous siRNAs derived from transposable elements

Darren J Obbard et al. Curr Biol. .
Free article

Abstract

The Piwi-interacting RNA interference pathway plays an important role in suppressing transposable elements in the Drosophila germline. Now, deep sequencing of short RNAs from somatic tissue and cell culture has identified a novel class of endogenous siRNAs that may have a similar role in the soma.

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