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Comment
. 2008 Jul;15(1):7-8.
doi: 10.1016/j.devcel.2008.06.008.

Leading Wnt down a PCP path: Cthrc1 acts as a coreceptor in the Wnt-PCP pathway

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Leading Wnt down a PCP path: Cthrc1 acts as a coreceptor in the Wnt-PCP pathway

Matthew W Kelley. Dev Cell. 2008 Jul.
Free article

Abstract

Wnt signaling regulates many aspects of development through canonical and PCP signaling pathways. A paper by Yamamoto et al. in this issue of Developmental Cell identifies collagen triple helix repeat containing 1 as a Wnt-binding cofactor that specifically activates the Wnt-PCP pathway.

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