Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2008 Jun;29(3):157-62.
doi: 10.1007/s10072-008-0928-z. Epub 2008 Jul 9.

Relationship between clinical examination, quality of life, disability and depression in CMT patients: Italian multicenter study

L Padua  1 , I Aprile, T Cavallaro, I Commodari, D Pareyson, A Quattrone, N Rizzuto, G Vita, P Tonali, A Schenone; Italian CMT QoL Study Group
Collaborators, Affiliations
Multicenter Study

Relationship between clinical examination, quality of life, disability and depression in CMT patients: Italian multicenter study

L Padua et al. Neurol Sci. 2008 Jun.

Abstract

Objective: To assess which are the clinical examination tests that are more related to quality of life (QoL), depression, and disability in CMT patients.

Design: Large prospective multicenter study through the use of validated clinical, disability, and QoL measurements. Correlations between clinical pattern and disability/QoL and depression were studied.

Setting: Departments of Neurology.

Patients and participants: 211 CMT patients (60% females, mean age 42.5 years).

Interventions: None.

Measurements and results: Sensory function was related to both mental and physical aspects of patient's QoL. Ability to walk on toes and heels was related to physical aspects of QoL/disability but also to bodily pain. Strength of forearm/hand intrinsic muscles was related to disability and physical aspects of QoL.

Conclusions: Some clinical tests may be better outcome measures than others because they are related to aspects of life highly relevant to the patients. This information may be useful in clinical practice and in clinical trials to infer the patient's QoL.

PubMed Disclaimer

References

    1. Md State Med J. 1965 Feb;14:61-5 - PubMed
    1. J Clin Epidemiol. 1998 Nov;51(11):1025-36 - PubMed
    1. Neurology. 2005 Apr 12;64(7):1209-14 - PubMed
    1. Brain. 1997 Mar;120 ( Pt 3):465-78 - PubMed
    1. Neurology. 2005 Sep 27;65(6):922-4 - PubMed

Publication types

MeSH terms

LinkOut - more resources