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Comment
. 2008 Jul 11;134(1):22-4.
doi: 10.1016/j.cell.2008.06.043.

The mitochondrial proteome: from inventory to function

Chris Meisinger  1 , Albert Sickmann, Nikolaus Pfanner
Affiliations
Free article
Comment

The mitochondrial proteome: from inventory to function

Chris Meisinger et al. Cell. .
Free article

Abstract

Mitochondria are central to cellular energetics, metabolism, and signaling. In this issue, Pagliarini et al. (2008) report the largest compendium of mammalian mitochondrial proteins to date. Together with proteomic studies in yeast, this study represents an important step toward the systematic characterization of the mitochondrial proteome and of mitochondrial diseases.

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  • A mitochondrial protein compendium elucidates complex I disease biology.
    Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, Mootha VK. Pagliarini DJ, et al. Cell. 2008 Jul 11;134(1):112-23. doi: 10.1016/j.cell.2008.06.016. Cell. 2008. PMID: 18614015 Free PMC article.

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