Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Aug-Sep;12(7):433-50.
doi: 10.1007/BF02982704.

Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives

Y Rolland  1 , S Czerwinski, G Abellan Van Kan, J E Morley, M Cesari, G Onder, J Woo, R Baumgartner, F Pillard, Y Boirie, W M C Chumlea, B Vellas
Affiliations
Review

Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives

Y Rolland et al. J Nutr Health Aging. 2008 Aug-Sep.

Abstract

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Sarcopenia and the disability process
Figure 2
Figure 2
Relationship between muscle mass, muscle strength and physical performances
See this image and copyright information in PMC

References

    1. Landi F, et al. Body mass index and mortality among older people living in the community. J Am Geriatr Soc. 1999;47(9):1072–6. - PubMed
    1. Rosenberg Summary comments. Am J Clin Nutr. 1989;(50):1231–3.
    1. Schwartz RS. Sarcopenia and physical performance in old age: introduction. Muscle Nerve Suppl. 1997;5:S10–2. - PubMed
    1. Hughes VA, et al. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr. 2002;76(2):473–81. - PubMed
    1. Vandervoort AA. Aging of the human neuromuscular system. Muscle Nerve. 2002;25(1):17–25. - PubMed