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. 2008 Oct;102(10):1053-4.
doi: 10.1016/j.trstmh.2008.06.001. Epub 2008 Jul 9.

A case series of dengue fever with altered consciousness and electroencephalogram changes in Sri Lanka

S A M Kularatne  1 , M M K Pathirage, S Gunasena
Affiliations

A case series of dengue fever with altered consciousness and electroencephalogram changes in Sri Lanka

S A M Kularatne et al. Trans R Soc Trop Med Hyg. 2008 Oct.

Abstract

We describe six serology-positive dengue patients presenting sporadically over 8 years, who lapsed into coma and showed generalized irregular slow waves in consecutive electroencephalograms (EEG) in the absence of any structural brain damage. The mean age was 41 years (range 16-65). All had fever, headache and vomiting for 3 days (range 2-4) on admission and developed coma after 24 h. Five patients developed generalized convulsions and two showed generalized paroxysmal spike-wave discharges in the EEG. All regained normal consciousness within 36 h. In two patients, slow waves in the EEG persisted for 6 and 18 months.

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