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. 2008 Oct;32(7):539-43.
doi: 10.1016/j.compmedimag.2008.06.001. Epub 2008 Jul 9.

Diffusion-weighted imaging of primary brain lymphomas: effect of ADC value and signal intensity of T2-weighted imaging

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Diffusion-weighted imaging of primary brain lymphomas: effect of ADC value and signal intensity of T2-weighted imaging

Masuma Akter et al. Comput Med Imaging Graph. 2008 Oct.

Abstract

The purpose of this study was to determine whether apparent diffusion coefficient (ADC) value and T2 signal intensity (SI) in primary brain lymphomas affect their SI on diffusion-weighted images (DWI). On DWI of 16 brain lesions of 16 patients, 9 (56.2%) were hyperintense (grade-3), 4 (25%) partially hyperintense (grade-2) and 3 (18.8%) isointense (grade-1). The mean ADC value of grade-3 lesions was significantly lower than of grade-1 lesions (p=0.028). The grade-1 lesions had ADC values of more than 0.8 and contrast-to-noise ratios of less than 18 on T2-weighted images. Their ADC value and T2 signal intensity affect their SI on DWI.

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