Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Aug;35(2 Suppl):S141-50.
doi: 10.1016/j.amepre.2008.05.006.

The social determinants of cancer: a challenge for transdisciplinary science

Affiliations

The social determinants of cancer: a challenge for transdisciplinary science

Robert A Hiatt et al. Am J Prev Med. 2008 Aug.

Abstract

To make further significant advances in cancer control research, a transdisciplinary science approach is needed that integrates the study of the biological nature of cancer and its clinical applications with the behavioral and social influences on cancer. More-effective interventions to reduce the burden of cancer can be developed and implemented by the adoption of a transdisciplinary research framework that takes into account the social determinants of cancer and seeks to discover interactions among social, environmental, behavioral, and biological factors in cancer etiology. This paper addresses two critical issues in the science of team science: (1) a cross-disciplinary, multilevel framework for organizing future research, and (2) a perspective that could aid in the translation and dissemination of cancer research findings in health care and public health practice. This conceptual framework is designed to encourage transdisciplinary research that will integrate social determinants into cancer research. The authors' goal is to promote a more complete understanding of the causes of cancer that will lead to the improved translation and implementation of the results of research.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Social determinants of cancer. Framework illustrates how social determinants relate to other levels of analysis and types of interventions along the cancer continuum. Healthcare systems are less likely to influence cancer incidence than mortality and are lightly shaded in the preclinical phase of the continuum.

References

    1. Howe HL, Wu X, Ries LA, et al. Annual report to the nation on the status of cancer, 1975– 2003, featuring cancer among U.S. Hispanic/Latino populations. Cancer 2006;107:1711–42. - PubMed
    1. Brown ML, Lipscomb J, Snyder C. The burden of illness of cancer: economic cost and quality of life. Annu Rev Public Health 2001;22:91–113. - PubMed
    1. Smedley BD, Syme SL, Committee on Capitalizing on Social Science and Behavioral Research to Improve the Public’s Health. Promoting health: intervention strategies from social and behavioral research. Am J Health Promot 2001;15(3):149–66. Comment in: Am J Health Promot 2001;15(3):iii–v. - PubMed
    1. Rosenfield PL. The potential of transdisciplinary research for sustaining and extending linkages between the health and social sciences. Soc Sci Med 1992;35(11):1343–57. - PubMed
    1. Nass SJ, Stillman B. Large-scale biomedical science: exploring strategies for future research. Washington DC: The National Academies Press, 2003.

MeSH terms