Langerhans cell dogma: another round of rejections
- PMID: 18626480
- DOI: 10.1038/jid.2008.167
Langerhans cell dogma: another round of rejections
Abstract
Mice that are deficient in epidermal Langerhans cells allow the functions of these cells in vivo to be rigorously assessed. Experiments that have been carried out with these animals have yielded surprising results, leading to major changes in existing paradigms. In this issue, Obhrai and coworkers explore the involvement of Langerhans cells in skin graft rejection and describe fascinating results.
Comment on
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Langerhans cells are not required for efficient skin graft rejection.J Invest Dermatol. 2008 Aug;128(8):1950-5. doi: 10.1038/jid.2008.52. Epub 2008 Mar 13. J Invest Dermatol. 2008. PMID: 18337832 Free PMC article.
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