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Comment
. 2008 Jul 18;29(1):1-2.
doi: 10.1016/j.immuni.2008.06.006.

ROS eliminate danger

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ROS eliminate danger

Marcus E Peter. Immunity. .
Free article

Abstract

Necrotic cells release HMGB1 as a danger signal to activate the immune system. In this issue of Immunity, Kazama et al. (2008) identify a mechanism that determines whether HMGB1 is tolerogenic or immunogenic.

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