gammadelta T cell selection: is anyone useless?
- PMID: 18631449
- DOI: 10.1016/j.immuni.2008.06.007
gammadelta T cell selection: is anyone useless?
Abstract
In this issue of Immunity, a study by Jensen et al. (2008) suggests that T cell-receptor engagement during development affects gammadelta T cell polarization toward either interferon-gamma or interleukin-17 production. This might underlie their unique innate ability to regulate inflammation.
Comment on
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  Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma.Immunity. 2008 Jul 18;29(1):90-100. doi: 10.1016/j.immuni.2008.04.022. Epub 2008 Jun 26. Immunity. 2008. PMID: 18585064 Free PMC article.
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