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Comment
. 2008 Jul 22;105(29):9851-2.
doi: 10.1073/pnas.0805207105. Epub 2008 Jul 16.

Reconstituting plant miRNA biogenesis

Jian-Kang Zhu  1
Affiliations
Comment

Reconstituting plant miRNA biogenesis

Jian-Kang Zhu. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
miRNA biogenesis and function in plants. Primary miRNA transcript is processed by the RNaseIII enzyme DCL1 (containing two double-stranded RNA-binding domains) and its associated RNA-binding cofactors HYL1 (containing two double-stranded RNA-binding domains) and SE (a C2H2-type zinc finger) to generate a miRNA, which is then methylated, exported to the cytoplasm and incorporated into the Agonaute 1 (AGO1)-containing RNA-induced silencing complex (RISC) to silence mRNA targets important for development, diseases, and stress responses.
See this image and copyright information in PMC

Comment on

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