Review
doi: 10.1093/hmg/ddn149.
Epigenetic regulation of stem cell fate
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- PMID: 18632693
- DOI: 10.1093/hmg/ddn149
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Review
Epigenetic regulation of stem cell fate
Hum Mol Genet.
.
Abstract
Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different cell types. However, this research is only the tip of the iceberg when it comes to writing an 'epigenetic instruction manual' for the ramification of molecular details of cell commitment and differentiation. In this review, we discuss the impact of the epigenetic research on our understanding of stem cell biology.
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