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Review
. 2008 Mar;26(1):112-21.

Rickets: an overview and future directions, with special reference to Bangladesh. A summary of the Rickets Convergence Group meeting, Dhaka, 26-27 January 2006

Thierry Craviari  1 , John M Pettifor, Tom D Thacher, Craig Meisner, Josiane Arnaud, Philip R Fischer; Rickets Convergence Group
Affiliations
Review

Rickets: an overview and future directions, with special reference to Bangladesh. A summary of the Rickets Convergence Group meeting, Dhaka, 26-27 January 2006

Thierry Craviari et al. J Health Popul Nutr. 2008 Mar.

Abstract

Rickets has emerged as a public-health problem in Bangladesh during the past two decades, with up to 8% of children clinically affected in some areas. Insufficiency of dietary calcium is thought to be the underlying cause, and treatment with calcium (350-1,000 mg elemental calcium daily) is curative. Despite this apparently simple treatment, little is known about the most appropriate management of bone deformities of affected children, and further studies are needed to determine the details of dosing and duration of calcium therapy, the role of bracing, and specific indications for surgical intervention. Effective preventive measures that can feasibly reach entire communities are needed, and these may differ between various affected regions.

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Figures

Fig. 1
Fig. 1
Clinical features of rickets
Fig. 2
Fig. 2
Clinical features of rickets: leg-deformities
Fig. 3
Fig. 3
Evolution of rickets deformities without treatment
Fig. 4
Fig. 4
Response of rachitic deformities with medical treatment
Fig. 5
Fig. 5
Graded treatment proposal for children with calcium-deficiency rickets
See this image and copyright information in PMC

References

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    1. Thacher TD. In: Hochberg Z, editor. Vitamin D and rickets. Basel: Karger; 2003. Calcium-deficiency rickets; pp. 105–25.
    1. Thacher TD, Fischer PR, Strand MA, Pettifor JM. Nutritional rickets around the world: causes and future directions. Ann Trop Paediatr. 2006;26:1–16. - PubMed
    1. Deadly bone diseases threaten Bangladesh. New Nation (Dhaka) 2000 Nov 26:1.
    1. 5m children affected by rickets. Daily Star (Dhaka) 2006 Jan 27;16(14). (http://www.thedailystar.net/ 2006/01/27/d60127060759.htm).

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