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Clinical Trial
. 1991 Jun;33(6):524-34.
doi: 10.1111/j.1469-8749.1991.tb14917.x.

Cognitive impairment in new cases of epilepsy randomly assigned to carbamazepine, phenytoin and sodium valproate

I Forsythe  1 , R Butler, I Berg, R McGuire
Affiliations
Clinical Trial

Cognitive impairment in new cases of epilepsy randomly assigned to carbamazepine, phenytoin and sodium valproate

I Forsythe et al. Dev Med Child Neurol. 1991 Jun.

Abstract

Sixty-four new cases of childhood epilepsy were randomly assigned to either carbamazepine, phenytoin or sodium valproate, and were assessed with cognitive tests before medication and three subsequent times over a year. Carbamazepine in moderate dosage adversely affected memory, but sodium valproate and phenytoin did not.

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