Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1991 Jul;87(3):245-53.
doi: 10.1007/BF00200899.

Prospects for homologous recombination in human gene therapy

M A Vega  1
Affiliations
Review

Prospects for homologous recombination in human gene therapy

M A Vega. Hum Genet. 1991 Jul.

Abstract

The ideal approach to gene therapy of hereditary diseases or gene correction therapy is considered. The advantages, disadvantages and limits of gene targeting by homologous recombination are discussed with regard to its possible application in gene correction therapy and in comparison with retroviral-mediated gene complementation therapy.

PubMed Disclaimer

References

    1. Mol Cell Biol. 1985 Oct;5(10):2599-607 - PubMed
    1. Science. 1990 Sep 14;249(4974):1285-8 - PubMed
    1. Prog Med Virol. 1987;34:1-32 - PubMed
    1. Nucleic Acids Res. 1988 Feb 11;16(3):941-52 - PubMed
    1. Nature. 1986 Nov 6-12;324(6092):34-8 - PubMed

LinkOut - more resources