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Case Reports
. 2008 Jun;28(3):150-3.

Pleomorphic adenoma of the lateral nasal wall: case report

D Sciandra  1 , F Dispenza, R Porcasi, G Kulamarva, C Saraniti
Affiliations
Case Reports

Pleomorphic adenoma of the lateral nasal wall: case report

D Sciandra et al. Acta Otorhinolaryngol Ital. 2008 Jun.

Abstract
in English, Italian

Pleomorphic adenoma is the most common tumour of the salivary glands. However, it is extremely rare for these to originate in the nose and even when they do so, it is most commonly in the nasal septum. It is important to be aware of the paucity of presenting symptoms (nasal obstruction and epistaxis), as the lesion may not be recognized immediately. Growth is generally restricted locally and the tumour is not known to spread to the neighbouring structures. Surgical resection is the treatment of choice. Recurrences and evolution to malignancy are not frequent, but long-term follow-up is recommended. The case is presented of pleomorphic adenoma arising from the lateral wall of the right nasal cavity, in a 34-year-old male, which was resected completely, endoscopically. Histological and immunohistochemical evaluation revealed the presence of a pleomorphic adenoma.

L’adenoma pleomorfo è il tumore benigno più comune delle ghiandole salivari. Comunque, la sua localizzazione nasale è molto rara e più comunemente origina dal setto. Importante è considerare che i sintomi di presentazione sono molto scarsi (ostruzione nasale e epistassi), per cui la lesione può decorrere a lungo misconosciuta. La crescita è generalmente locale e non sono noti casi di diffusione nelle strutture adiacenti. La resezione chirurgica è il trattamento di scelta. La recidiva e l’evoluzione maligna non sono frequenti, ma un lungo follow-up è da raccomandare. Presentiamo un caso di adenoma pleomorfo ad origine dalla parete laterale della fossa nasale di destra in un paziente di 34 anni, trattato chirurgicamente con resezione endoscopica completa. La valutazione istologica ed immunoistochimica hanno dimostrato la presenza di un adenoma pleomorfo.

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Figures

Fig. 1
Fig. 1
Axial CT scan showing soft density mass in anterior portion of right nasal fossa with thinness of nasal process of maxillary bone.
Fig. 2
Fig. 2
Epithelial structures showing solid, trabecular and cystic patterns intermingled with myxoid stroma (H&E, x250).
Fig. 3
Fig. 3
Immunostaining for smooth muscle actin (x 250).
Fig. 4
Fig. 4
Immunostaining for S100 protein (x 400).
See this image and copyright information in PMC

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