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. 2008 Jul 22:8:251.
doi: 10.1186/1471-2458-8-251.

Metabolic syndrome as a cardiovascular disease risk factor: patients evaluated in primary care

Joan-Josep Cabré  1 , Francisco Martín, Bernardo Costa, Josep L Piñol, Josep L Llor, Yolanda Ortega, Josep Basora, Marta Baldrich, Rosa Solà, Jordi Daniel, Josep Ma Hernández, Judit Saumell, Jordi Bladé, Ramon Sagarra, Teresa Basora, Dolors Montañés, Joan L Frigola, Angel Donado-Mazarrón, Maria Teresa García-Vidal, Isabel Sánchez-Oro, Josep M de Magriñà, Ana Urbaneja, Francisco Barrio, Jesús Vizcaíno, Josep M Sabaté, Irene Pascual, Vanesa Revuelta
Affiliations

Metabolic syndrome as a cardiovascular disease risk factor: patients evaluated in primary care

Joan-Josep Cabré et al. BMC Public Health. .

Abstract

To estimate the prevalence of metabolic syndrome (MS) in a population receiving attention in primary care centers (PCC) we selected a random cohort of ostensibly normal subjects from the registers of 5 basic-health area (BHA) PCC. Diagnosis of MS was with the WHO, NCEP and IDF criteria. Variables recorded were: socio-demographic data, CVD risk factors including lipids, obesity, diabetes, blood pressure and smoking habit and a glucose tolerance test outcome. Of the 720 individuals selected (age 60.3 +/- 11.5 years), 431 were female, 352 hypertensive, 142 diabetic, 233 pre-diabetic, 285 obese, 209 dyslipemic and 106 smokers. CVD risk according to the Framingham and REGICOR calculation was 13.8 +/- 10% and 8.8 +/- 9.8%, respectively. Using the WHO, NCEP and IDF criteria, MS was diagnosed in 166, 210 and 252 subjects, respectively and the relative risk of CVD complications in MS subjects was 2.56. Logistic regression analysis indicated that the MS components (WHO set), the MS components (IDF set) and the female gender had an increased odds ratio for CVD of 3.48 (95CI%: 2.26-5.37), 2.28 (95%CI: 1.84-4.90) and 2.26 (95%CI: 1.48-3.47), respectively. We conclude that MS and concomitant CVD risk is high in ostensibly normal population attending primary care clinics, and this would necessarily impinge on resource allocation in primary care.

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Figures

Figure 1
Figure 1
Flow chart of the study: Prospective, multi-centered cohort study to evaluate the cardiovascular disease event associated with metabolic syndrome in a randomly selected study sample.
Figure 2
Figure 2
Cardiovascular disease (CVD) events segregated with respect to number of components of metabolic syndrome (MS); NCEP criteria.
Figure 3
Figure 3
Cardiovascular disease (CVD) events segregated with respect to number of components of metabolic syndrome (MS): WHO criteria; * = alterations in glucose metabolism not included in the components.
Figure 4
Figure 4
Cardiovascular disease (CVD) events segregated with respect to number of components of metabolic syndrome (MS); IDF criteria.
See this image and copyright information in PMC

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