[Fournier's gangrene--a model of necrotizing fasciitis (clinical and pathogenetic aspects)]
- PMID: 18649664
[Fournier's gangrene--a model of necrotizing fasciitis (clinical and pathogenetic aspects)]
Abstract
Pathogenesis of Fournier's disease was studied pathomorphologically and pathophysiologically. The underlying factor is thrombosis of the microcirculatory bed of the superficial fascia progressing into ischemic and hypoperfusion necrosis of the fascial structures manifesting with severe endotoxicosis and development of polyorganic insufficiency.