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. 2008 Jul 22;5(7):e156.
doi: 10.1371/journal.pmed.0050156.

Evidence-based tuberculosis diagnosis

Madhukar Pai  1 , Andrew Ramsay, Richard O'Brien
Affiliations

Evidence-based tuberculosis diagnosis

Madhukar Pai et al. PLoS Med. .

Abstract

Madhukar Pai and colleagues discuss how systematic reviews on tuberculosis diagnostics can influence research, policy, and clinical practice.

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Conflict of interest statement

Competing Interests: The authors have no financial conflicts of interest. All the authors are members of the Stop TB Partnership's Working Group on New Diagnostics. AR is the secretary of the Working Group. MP and ROB are co-chairs of the Working Group's subgroup on Evidence Synthesis for TB Diagnostics. ROB works for the Foundation for Innovative New Diagnostics, a nonprofit agency that collaborates with several industry partners for the development of new diagnostics for neglected infectious diseases. No industry partner was involved in the preparation of this manuscript.

Figures

Figure 1
Figure 1. Low-Cost LED-Based Fluorescence Microscopy Being Evaluated at a TDR/WHO Trial Site in Abuja, Nigeria
Photographer: Andrew Ramsay (Courtesy of TDR, Geneva)
Figure 2
Figure 2. A Simplified NAAT Being Evaluated at a FIND Trial Site in India
Photographer: Ralf Linke (Courtesy of FIND, Geneva)
See this image and copyright information in PMC

References

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    1. World Health Organization. New technologies for tuberculosis control: A framework for their adoption, introduction and implementation. 2007. Available: http://whqlibdoc.who.int/publications/2007/9789241595520_eng.pdf. Accessed 16 June 2008.
    1. World Health Organization, Special Programme for Research and Training in Tropical Diseases. Diagnostics for tuberculosis. Global demand and market potential. 2006. Available: http://www.who.int/tdr/publications/publications/tbdi.htm. Accessed 16 June 2008.
    1. Oxman AD, Lavis JN, Fretheim A. Use of evidence in WHO recommendations. Lancet. 2007;369:1883–1889. - PubMed

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