[Behcet's disease]

Abstract

The results of observation of 83 patients with Behcet's disease (BD) are represented. BD is included into the group of systemic vasculites with unknown etiology. Clinical manifestations of the disease are multiform. According to international criteria, suggested in 1990 year among examined by us BD patients the disease often is characterized by major diagnostic criteria: relapsing aphthous stomatitis, ulcerous lesion of genitals and ocular lesions. There are also small diagnostic criteria which include: disturbances of central nervous system (CNS), gastrointestinal tract (GIT), vascular pathology (arterial and venous thromboses), articular pathology e. a. The frequency of minor BD criteria is rather lower, but CNS and GIT disturbances and thromboses often determine the vital prognosis of the disease. We revealed that males suffer more often than females m:f = 1.7:1. Association between BD and HLA B5 antigen was found in 85.5% patients.