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Review
. 2008 Aug;25(4):757-93.
doi: 10.1039/b801747f. Epub 2008 May 23.

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

Elizabeth S Sattely  1 , Michael A Fischbach, Christopher T Walsh
Affiliations
Review

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

Elizabeth S Sattely et al. Nat Prod Rep. 2008 Aug.

Abstract

This review surveys efforts to reconstitute key steps in polyketide and nonribosomal peptide biosynthetic pathways with purified enzymes and substrates; 344 references are cited.

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