Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Sep;4(3):211-6.
doi: 10.1007/s12015-008-9037-x. Epub 2008 Jul 29.

Targeting cancer stem cells in cancer prevention and therapy

Prithi Rajan  1 , Roopa Srinivasan
Affiliations
Review

Targeting cancer stem cells in cancer prevention and therapy

Prithi Rajan et al. Stem Cell Rev. 2008 Sep.

Abstract

The cancer stem cell hypothesis is an attractive framework within which one may think about cancer initiation, recurrence, and metastasis, and methods to devise treatment strategies for cancers. Although all cancers do not appear to sustain themselves with cancer stem cells, but also through a dominant cell population, creating strategies for cancer treatment which include cancer stem cells as targets seems reasonable. In this perspective we discuss possible strategies for controlling the viability and tumorigenecity of cancer stem cells, and extend our discussion to strategies approaching the prevention of cancer.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Neurosurg Clin N Am. 2007 Jan;18(1):81-92, ix - PubMed
    1. Nat Immunol. 2002 Nov;3(11):991-8 - PubMed
    1. Nature. 2006 Dec 7;444(7120):761-5 - PubMed
    1. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3983-8 - PubMed
    1. J Exp Med. 2003 Dec 1;198(11):1753-7 - PubMed

MeSH terms

LinkOut - more resources