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. 2009 Apr;34(3):317-27.
doi: 10.1093/jpepsy/jsn080. Epub 2008 Jul 30.

Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia

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Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia

Laura K Campbell et al. J Pediatr Psychol. 2009 Apr.

Abstract

Objective: To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors.

Methods: We examined associations among several domains of executive function (working memory, behavioral inhibition, cognitive flexibility, and self-monitoring), coping, and emotional/behavioral problems in 30 children and adolescents ages 10- to 20-years old who completed treatment for ALL and 30 healthy controls matched on age and sex.

Results: We found partial support for our hypothesis that performance on executive function measures is associated with strategies used to cope with stress, and emotional and behavioral problems in ALL survivors.

Conclusions: Findings suggest that executive function impairment may be associated with difficulties in coping and emotion regulation in a subgroup of children treated for ALL. Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.

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Figures

Figure 1.
Figure 1.
Secondary control coping fully mediated the relationship between three of the four EF domains (working memory, cognitive flexibility, and self-monitoring) and total behavior problems in the ALL group.

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