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Review

. 2008 Aug;66 Suppl 1(Suppl 1):S36-8.

doi: 10.1111/j.1753-4887.2008.00065.x.

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

Roderick H Dashwood¹, Emily Ho

Affiliations

Affiliation

¹ The Linus Pauling Institute, Department of Environmental and Molecular Toxicology, and Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, Oregon 97331, USA. rod.dashwood@oregonstate.edu

PMID: 18673487
PMCID: PMC2656672
DOI: 10.1111/j.1753-4887.2008.00065.x

Review

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

Roderick H Dashwood et al. Nutr Rev. 2008 Aug.

. 2008 Aug;66 Suppl 1(Suppl 1):S36-8.

doi: 10.1111/j.1753-4887.2008.00065.x.

Authors

Roderick H Dashwood¹, Emily Ho

Affiliation

¹ The Linus Pauling Institute, Department of Environmental and Molecular Toxicology, and Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, Oregon 97331, USA. rod.dashwood@oregonstate.edu

PMID: 18673487
PMCID: PMC2656672
DOI: 10.1111/j.1753-4887.2008.00065.x

No abstract available

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References

1. Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci. 2007;64:1105–1127. - PMC - PubMed
1. Myzak M, Dashwood RH. Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Lett. 2006;233:208–218. - PMC - PubMed
1. Xu WS, Parmigiani WB, Marks PA. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene. 2007;26:5541–5552. - PubMed
1. Dashwood RH, Myzak MC, Ho E. Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis. 2006;27:344–349. - PMC - PubMed
1. Myzak MC, Karplus PA, Chung FL, Dashwood RH. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res. 2004;64:5767–5774. - PubMed

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