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Case Reports
. 1991 Aug;109(8):1104-8.
doi: 10.1001/archopht.1991.01080080064029.

Mizuo phenomenon in X-linked retinoschisis. Pathogenesis of the Mizuo phenomenon

P T de Jong  1 , E Zrenner, G J van Meel, J E Keunen, D van Norren
Affiliations
Case Reports

Mizuo phenomenon in X-linked retinoschisis. Pathogenesis of the Mizuo phenomenon

P T de Jong et al. Arch Ophthalmol. 1991 Aug.

Abstract

Four unrelated males with X-linked retinoschisis and a golden fundus reflex had Mizuo-Nakamura phenomenon, which, to our knowledge, has been described only in Oguchi's disease and X-linked cone dystrophy. These findings, together with experimental observations and data from the literature, led us to hypothesize that the Mizuo-Nakamura phenomenon is caused by an excess of extracellular potassium in the retina as a result of a decreased potassium scavenging capacity of retinal Müller cells.

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