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. 1976 Oct;3(10):2521-8.
doi: 10.1093/nar/3.10.2521.

Identification of the minor guanylated tRNA of rabbit reticulocytes

W R Farkas, D Chernoff
Free PMC article

Identification of the minor guanylated tRNA of rabbit reticulocytes

W R Farkas et al. Nucleic Acids Res. 1976 Oct.
Free PMC article

Abstract

Two of the tRNA's found in rabbit reticulocytes are substrates for a post-transcriptional modification leading to the incorporation of guanine into the polynucleotide chain. The major guanylated tRNA was previously identified as tRNA (His). In the present report we show that the minor guanylated tRNA is tRNA (Asn), and that just as in the case of tRNA (His), the guanine is located in an internal position. There are only two tRNA (Asn) in reticulocytes. We further show that one of these, the one that is not labeled with guanine, contains the hypermodified base known as Q. tRNA (Asn) does not contain Q.

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References

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