Comment in

• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. The real cause of exercise limitation in COPD.

  Wagner PD. Wagner PD. J Appl Physiol (1985). 2008 Aug;105(2):758. doi: 10.1152/japplphysiol.90336.2008c. J Appl Physiol (1985). 2008. PMID: 18678625 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Interpretation of exercise intolerance in COPD requires an integrated, multisystemic approach.

  Neder JA. Neder JA. J Appl Physiol (1985). 2008 Aug;105(2):758-9. doi: 10.1152/japplphysiol.90336.2008e. J Appl Physiol (1985). 2008. PMID: 18678626 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Might an imbalance between energy supplies and demands curtail incremental exercise in Gold stage I COPD patients?

  Scano GL. Scano GL. J Appl Physiol (1985). 2008 Aug;105(2):759. doi: 10.1152/japplphysiol.90336.2008d. J Appl Physiol (1985). 2008. PMID: 18678627 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Defining 'dynamic hyperinflation'.

  West JB. West JB. J Appl Physiol (1985). 2008 Aug;105(2):758. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18678628 No abstract available.
• Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation.

  Aliverti A, Macklem PT. Aliverti A, et al. J Appl Physiol (1985). 2008 Aug;105(2):763. doi: 10.1152/japplphysiol.90745.2008. J Appl Physiol (1985). 2008. PMID: 18678629 No abstract available.
• Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation.

  Debigaré R, Maltais F. Debigaré R, et al. J Appl Physiol (1985). 2008 Aug;105(2):764. doi: 10.1152/japplphysiol.90758.2008. J Appl Physiol (1985). 2008. PMID: 18678630 No abstract available.
• Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation.

  O'Donnell D, Webb K. O'Donnell D, et al. J Appl Physiol (1985). 2008 Aug;105(2):765. doi: 10.1152/japplphysiol.90739.2008. J Appl Physiol (1985). 2008. PMID: 18678631 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Measurements, estimates, interpretations, myths.

  Jones NL. Jones NL. J Appl Physiol (1985). 2008 Aug;105(2):759-60. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770880 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Exercise intolerance in COPD: putting the pieces of the puzzle together.

  Zakynthinos SG, Vogiatzis I. Zakynthinos SG, et al. J Appl Physiol (1985). 2008 Aug;105(2):760. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770881 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Difficulties in determining the primary physiological abnormality that limits exercise performance in COPD.

  Nici L. Nici L. J Appl Physiol (1985). 2008 Aug;105(2):760-1. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770882 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Multiple mechanisms limit exercise in COPD.

  Calverley PM. Calverley PM. J Appl Physiol (1985). 2008 Aug;105(2):761. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770883 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. Missing pieces.

  Gosker HR, Schols AM. Gosker HR, et al. J Appl Physiol (1985). 2008 Aug;105(2):761. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770884 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. "In medio stat virtus.".

  Palange P. Palange P. J Appl Physiol (1985). 2008 Aug;105(2):762. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770885 No abstract available.
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation. There is no magic bullet in COPD.

  Marciniuk DD. Marciniuk DD. J Appl Physiol (1985). 2008 Aug;105(2):762. doi: 10.1152/japplphysiol.zdg-8100.pcpcomm.2008. J Appl Physiol (1985). 2008. PMID: 18770886 No abstract available.