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. 2008 Aug;14(8):1300-2.
doi: 10.3201/eid1408.080444.

Genotyping Rickettsia prowazekii isolates

Yong Zhu  1 , Aaron Medina-Sanchez, Donald Bouyer, David H Walker, Xue-Jie Yu
Affiliations

Genotyping Rickettsia prowazekii isolates

Yong Zhu et al. Emerg Infect Dis. 2008 Aug.

Abstract

We developed a typing method that can differentiate 8 strains of Rickettsia prowazekii into 7 genotypes. This method can be used to type and trace the origin of R. prowazekii isolated from samples collected during epidemics after a bioterrorism attack.

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Figures

Figure
Figure
Phylogenic tree of Rickettsia prowazekii strains generated by using the concatenated sequences of 6 loci from each strain. R. typhi sequences were used to root the tree.
See this image and copyright information in PMC

References

    1. Raoult D, Woodward T, Dumler JS. The history of epidemic typhus. Infect Dis Clin North Am. 2004;18:127–40. 10.1016/S0891-5520(03)00093-X - DOI - PubMed
    1. Raoult D, Roux V, Ndihokubwayo JB, Bise G, Baudon D, Marte G, et al. Jail fever (epidemic typhus) outbreak in Burundi. Emerg Infect Dis. 1997;3:357–60. - PMC - PubMed
    1. Bozeman FM, Sonenshine DE, Williams MS, Chadwick DP, Lauer DM, Elisberg BL. Experimental infection of ectoparasitic arthropods with Rickettsia prowazekii (GvF-16 strain) and transmission to flying squirrels. Am J Trop Med Hyg. 1981;30:253–63. - PubMed
    1. Duma RJ, Sonenshine DE, Bozeman FM, Veazey JM Jr, Elisberg BL, Chadwick DP, et al. Epidemic typhus in the United States associated with flying squirrels. JAMA. 1981;245:2318–23. 10.1001/jama.245.22.2318 - DOI - PubMed
    1. Andersson SG, Zomorodipour A, Andersson JO, Sicheritz-Ponten T, Alsmark UC, Podowski RM, et al. The genome sequence of Rickettsia prowazekii and the origin of mitochondria. Nature. 1998;396:133–40. 10.1038/24094 - DOI - PubMed

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