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Review
. 2008 Aug;139(8):1052-9.
doi: 10.14219/jada.archive.2008.0307.

Maxillary osteosarcoma associated with a dental implant: report of a case and review of the literature regarding implant-related sarcomas

H Stan McGuff  1 , Josefine Heim-Hall, F Christopher Holsinger, Archie A Jones, Daniel S O'Dell, Adam C Hafemeister
Affiliations
Review

Maxillary osteosarcoma associated with a dental implant: report of a case and review of the literature regarding implant-related sarcomas

H Stan McGuff et al. J Am Dent Assoc. 2008 Aug.

Abstract

Background: The development of malignant neoplasms has been reported as a rare complication of the use of implanted biomaterials. The majority of these cases have been sarcomas related to orthopedic hardware. The authors present the first reported case of a sarcoma arising in association with a dental implant.

Case description: A 38-year-old woman developed a low-grade chondroblastic osteosarcoma of the right maxilla 11 months after receiving a titanium dental implant. She was treated with systemic chemotherapy and then a maxillary resection. As of this publication, 47 months later, she is alive and disease-free.

Clinical implications: The use of endosseous implants has been associated with a low risk for the development of cancer. As the use of dental implants continues to expand, dentists need to be aware of this rare but devastating complication.

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