Can metformin undo weight gain induced by antipsychotics?
- PMID: 18687228
- PMCID: PMC3183916
Can metformin undo weight gain induced by antipsychotics?
Abstract
Convincing evidence shows that metformin alone and in combination with lifestyle changes is superior to lifestyle changes alone or placebo
Comment on
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Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial.JAMA. 2008 Jan 9;299(2):185-93. doi: 10.1001/jama.2007.56-b. JAMA. 2008. PMID: 18182600 Clinical Trial.
References
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- Wu R-R, Zhao J-P, Jin H, et al. Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial. JAMA. 2008;299:185–193.. - PubMed
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- American Diabetes Association; American Psychiatric Association; American Association of Clinical Endocrinologists; North American Association for the Study of Obesity. Consensus development conference on antipsychotic drugs and obesity and diabetes. Diabetes Care. 2004;27:596–601.. - PubMed
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- Newcomer JW. Metabolic considerations in the use of antipsychotic medications: a review of recent evidence. J Clin Psychiatry. 2007;68(suppl 1):20–27.. - PubMed
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