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. 2008 Aug 8;321(5890):824-6.
doi: 10.1126/science.1157312.

Programming DNA tube circumferences

Peng Yin  1 , Rizal F Hariadi, Sudheer Sahu, Harry M T Choi, Sung Ha Park, Thomas H Labean, John H Reif
Affiliations
Free article

Programming DNA tube circumferences

Peng Yin et al. Science. .
Free article

Abstract

Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

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