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Review
. 2009 Jan;1793(1):20-6.
doi: 10.1016/j.bbamcr.2008.07.005. Epub 2008 Jul 21.

The molecular mechanism of mitochondrial fusion

Suzanne Hoppins  1 , Jodi Nunnari
Affiliations
Free article
Review

The molecular mechanism of mitochondrial fusion

Suzanne Hoppins et al. Biochim Biophys Acta. 2009 Jan.
Free article

Abstract

This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion.

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