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. 2008 Sep;44(13):1789-92.
doi: 10.1016/j.ejca.2008.06.037. Epub 2008 Aug 6.

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

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Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

A Rody et al. Eur J Cancer. 2008 Sep.

Abstract

Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.

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