Gazing at translocation in the mitochondrion
- PMID: 18692459
- DOI: 10.1016/j.cell.2008.07.024
Gazing at translocation in the mitochondrion
Abstract
Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondrion via molecular machines called translocons on the outer and inner mitochondrial membranes. Alder et al. (2008b) examine protein translocation into intact mitochondria by adapting fluorescent techniques first used to study translocation in the endoplasmic reticulum.
Comment on
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Fluorescence mapping of mitochondrial TIM23 complex reveals a water-facing, substrate-interacting helix surface.Cell. 2008 Aug 8;134(3):439-50. doi: 10.1016/j.cell.2008.06.007. Cell. 2008. PMID: 18692467
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