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Comment
. 2008 Aug 8;134(3):388-9.
doi: 10.1016/j.cell.2008.07.026.

Genome sequences from extinct relatives

Andrew G Clark  1
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Free article
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Genome sequences from extinct relatives

Andrew G Clark. Cell. .
Free article

Abstract

Next-generation sequencing methods use massively parallel detection of short sequencing reactions, making them ideal for the analysis of ancient DNA. In this issue, Green et al. (2008) exploit this feature to infer the complete mitochondrial genome sequence of one Neanderthal and place bounds on its time of common ancestry with modern humans.

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  • A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing.
    Green RE, Malaspinas AS, Krause J, Briggs AW, Johnson PL, Uhler C, Meyer M, Good JM, Maricic T, Stenzel U, Prüfer K, Siebauer M, Burbano HA, Ronan M, Rothberg JM, Egholm M, Rudan P, Brajković D, Kućan Z, Gusić I, Wikström M, Laakkonen L, Kelso J, Slatkin M, Pääbo S. Green RE, et al. Cell. 2008 Aug 8;134(3):416-26. doi: 10.1016/j.cell.2008.06.021. Cell. 2008. PMID: 18692465 Free PMC article.

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