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Review
. 2009 Apr;34(3):347-51.
doi: 10.1111/j.1365-2230.2008.02905.x. Epub 2008 Aug 9.

Sneddon-Wilkinson disease treated with etanercept: report of two cases

D R Berk  1 , M A Hurt, C Mann, D Sheinbein
Affiliations
Review

Sneddon-Wilkinson disease treated with etanercept: report of two cases

D R Berk et al. Clin Exp Dermatol. 2009 Apr.

Abstract

Sneddon-Wilkinson disease (SWD), also known as subcorneal pustular dermatosis, is a rare, chronic eruption that is often difficult to treat, particularly in patients who do not respond to or cannot tolerate dapsone. Few case reports exist of patients with SWD treated with antitumour necrosis factor-alpha therapy. We report two patients with SWD refractory to numerous treatments, who responded to etanercept (in combination with low-dose acitretin in one case).

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