Orphans against autoimmunity
- PMID: 18701076
- DOI: 10.1016/j.immuni.2008.07.008
Orphans against autoimmunity
Abstract
In this issue of Immunity, Hermann-Kleiter et al. (2008) identify a nuclear orphan receptor, NR2F6, as a negative regulator of the T helper 17 cell subset and report that NR2F6-deficient mice develop late-onset autoimmune disease.
Comment on
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The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.Immunity. 2008 Aug 15;29(2):205-16. doi: 10.1016/j.immuni.2008.06.008. Immunity. 2008. PMID: 18701084 Free PMC article.
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