Illuminating the black box of TNF action in tuberculous granulomas
- PMID: 18701080
- DOI: 10.1016/j.immuni.2008.07.003
Illuminating the black box of TNF action in tuberculous granulomas
Abstract
TNF clearly contributes to immunity to intracellular pathogens, but how it does so is incompletely understood. In this issue of Immunity, Clay et al. (2008) provide unique insights, using intravital microscopy and the zebrafish-embryo model of tuberculosis.
Comment on
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Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death.Immunity. 2008 Aug 15;29(2):283-94. doi: 10.1016/j.immuni.2008.06.011. Immunity. 2008. PMID: 18691913 Free PMC article.
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