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Review
. 2008 Sep;43(3):374-9.
doi: 10.1016/j.cyto.2008.07.014. Epub 2008 Aug 12.

Cytokines as a key component of cancer-related inflammation

Giovanni Germano  1 , Paola Allavena, Alberto Mantovani
Affiliations
Review

Cytokines as a key component of cancer-related inflammation

Giovanni Germano et al. Cytokine. 2008 Sep.

Abstract

Inflammatory conditions in some tissues increase the risk of cancer. Cytokines and chemokines are components of an intensive dialog promoting angiogenesis, metastasis, subversion of adaptive immunity and changing response to hormones and to chemotherapeutic agents. Cytokines involved in cancer-related inflammation represent a target for innovative diagnostic and therapeutic strategies, and a future challenge for scientists and clinicians.

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