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Review
. 2008 Aug;22(8):686-8.
doi: 10.1155/2008/671969.

Microscopic colitis: an approach to treatment

Nilesh Chande  1
Affiliations
Review

Microscopic colitis: an approach to treatment

Nilesh Chande. Can J Gastroenterol. 2008 Aug.

Abstract
in English, French

Microscopic colitis--including collagenous colitis and lymphocytic colitis--causes chronic watery diarrhea, usually in middle-aged or elderly patients. There is an association with celiac disease and certain medications. Medical treatment includes various antidiarrheal agents, mesalamine, corticosteroids and immunosuppressant drugs. Rarely, patients require surgery for refractory disease. An evidence-based and practical approach to treatment should optimize the treatment response while minimizing potential adverse events.

La colite microscopique, incluant la colite collagène et la colite lymphocytaire, provoque une diarrhée aqueuse chronique, généralement chez les patients d’âge mûr ou âgés. Il existe un lien entre la maladie cœliaque et certains médicaments. Le traitement médical inclut divers antidiarrhéiques, la mésalamine, les corticoïdes et les immunosuppresseurs. Dans de rares cas, les patients doivent subir une opération en raison d’une maladie réfractaire. Une approche thérapeutique probante et pratique devrait optimiser la réponse au traitement tout en réduisant au minimum le potentiel d’effets indésirables.

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