Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Aug 14;27(1):28.
doi: 10.1186/1756-9966-27-28.

Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature

Enrico M Zardi  1 , Francesco Di Matteo, Daniele Santini, Valentina Uwechie, Pierfilippo Crucitti, Massimiliano Carassiti, Antonio Picardi, Eleonora Perrella, Marco Caricato, Giuseppe Tonini, Roberto Coppola, Antonella Afeltra
Affiliations
Review

Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature

Enrico M Zardi et al. J Exp Clin Cancer Res. .

Abstract

Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis.

PubMed Disclaimer

References

    1. Tapani E, Taavitsainen M, Lindros K, Vehmas T, Lehtonen E. Toxicity of ethanol in low concentrations. Experimental evaluation in cell culture. Acta Radiol. 1996;37:923–926. - PubMed
    1. Redvanly RD, Chezmar JL, Strauss RM, Galloway JR, Boyer TD, Bernardino ME. Malignant hepatic tumors: safety of high-dose percutaneous ethanol ablation therapy. Radiology. 1993;188:283–85. - PubMed
    1. Tapani E, Soiva M, Lavonen J, Ristkari S, Vehmas T. Complications following high-dose percutaneous ethanol injection into hepatic tumors. Acta Radiol. 1996;37:655–659. - PubMed
    1. Hastier P, Demarquay JF, Maes B, Caroli-Bosc FX, Dumas R, Delmont J, Chichmanian RM. Acute pancreatitis induced by codeine-acetaminophen association: a case report with positive rechallenge. Pancreas. 1996;13:324–326. doi: 10.1097/00006676-199610000-00017. - DOI - PubMed
    1. Hastier P, Longo F, Buckley M, Chichmanian RM, Delmont JP. Pancreatitis induced by codeine: a case report with positive rechallenge. Gut. 1997;41:705–706. - PMC - PubMed

MeSH terms