Transposed conditionals, shrinkage, and direct and indirect unbiasedness
- PMID: 18703929
- DOI: 10.1097/EDE.0b013e318181b3e3
Transposed conditionals, shrinkage, and direct and indirect unbiasedness
Abstract
Unbiasedness as conventionally understood is not a necessary property of good inferences. Such unbiasedness is "direct"--it guarantees that, on average, an estimate equals the thing it is estimating (the parameter). Strange as it may seem, this does not mean that the parameter is on average equal to its estimate. This would require the very different property of inverse unbiasedness. When this phenomenon is understood, shrinkage of results can be seen to be a necessary fact of life.
Comment on
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Why most discovered true associations are inflated.Epidemiology. 2008 Sep;19(5):640-8. doi: 10.1097/EDE.0b013e31818131e7. Epidemiology. 2008. PMID: 18633328 Review.
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