Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Jul;6(3):127-35.
doi: 10.2450/2008.0056-07.

Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura

Massimo Franchini  1 , Pier Mannuccio Mannucci
Affiliations
Review

Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura

Massimo Franchini et al. Blood Transfus. 2008 Jul.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
General principle of ADAMTS13 activity assays
Figure 2
Figure 2
Rates (%) of ADAMTS13 (partial or severe) in patients with clinically-diagnosed acute TTP
Figure 3a
Figure 3a
Remission rates (%) in patients with acute TTP with severe vs non-severe ADAMTS13 deficiency
Figure 3b
Figure 3b
Mortality rate (%) in patients with acute TTP with severe vs non-severe ADAMTS13 deficiency
Figure 4a
Figure 4a
Remission rates (%) in patients with acute TTP with or without anti-ADAMTS13
Figure 4b
Figure 4b
Mortality rate (%) in patients with acute TTP with or without anti-ADAMTS13
See this image and copyright information in PMC

References

    1. Tsai HM. Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura. J Am Soc Nephrol. 2003;14:1072–81. - PubMed
    1. Sadler JE, Moake JL, Miyata T, et al. Recent advances in thrombotic thrombocytopenic purpura. Hematology (Am Soc Hematol Educ Program) 2004:407–23. - PubMed
    1. Mannucci PM, Lavoretano S, Peyvandi S. The thrombotic microangiopathies. Blood Transf. 2005;3:120–35.
    1. Moschcowitz E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Proc NY Pathol Soc. 1924;24:21–4.
    1. Amorosi EL, Ultmann JE. Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine (Baltimore) 1966;45:139–59.

MeSH terms