doi: 10.1016/j.radonc.2008.07.018.
Epub 2008 Aug 14.
Hypoxia downregulates Ku70/80 expression in cervical carcinoma tumors
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- PMID: 18706726
- DOI: 10.1016/j.radonc.2008.07.018
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Hypoxia downregulates Ku70/80 expression in cervical carcinoma tumors
Radiother Oncol.
2008 Nov.
Abstract
Hypoxia may inhibits the NHEJ DNA repair through downregulating Ku70/80 expression and combined with an increased angiogenesis and altered p53 expression would be responsible for tumor progression in cervical carcinoma.
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