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Review
. 2008 Oct;44(1):9-13.
doi: 10.1016/j.cyto.2008.06.013. Epub 2008 Aug 15.

TIM-1 and TIM-3 proteins in immune regulation

Ee Wern Su  1 , Jean Y Lin, Lawrence P Kane
Affiliations
Review

TIM-1 and TIM-3 proteins in immune regulation

Ee Wern Su et al. Cytokine. 2008 Oct.

Abstract

Over the last several years, there has been increasing interest in the role of proteins of the TIM (T cell immunoglobulin and mucin domain) family in regulating immune responses. Despite what the name suggests, proteins of this family function in a much more widespread manner than just on T cells, as we will discuss in this review. We therefore propose that the definition of TIM be adjusted to "transmembrane immunoglobulin and mucin".

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References

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    1. McIntire JJ, Umetsu DT, DeKruyff RH. TIM-1, a novel allergy and asthma susceptibility gene. Springer Semin Immunopathol. 2004;25:335–348. - PubMed

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