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Comparative Study
. 2008 Aug:14 Suppl 4:8-13.

SARS coronavirus and apoptosis

K Y Chow  1 , Y S Yeung, C C Hon, F Zeng, K M Law, F C Leung
Affiliations
  • PMID: 18708667
Free article
Comparative Study

SARS coronavirus and apoptosis

K Y Chow et al. Hong Kong Med J. 2008 Aug.
Free article

Abstract

1. The adenovirus-mediated overexpression of SARS coronavirus (SARS-CoV) spike protein (S) and its C-terminal domain (S2) induce apoptosis in Vero E6 cells. 2. Such apoptosis in Vero E6 cells is time- and dose-dependent. 3. The adenovirus-mediated overexpression of SARS-CoV N-terminal domain (S1) and other structural proteins, including E,M and N protein, do not induce apoptosis.

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