Senescence: not just for tumor suppression
- PMID: 18724927
- DOI: 10.1016/j.cell.2008.08.003
Senescence: not just for tumor suppression
Abstract
Cellular senescence provides an intrinsic barrier to tumor development by preventing the proliferation of cells that are at risk for malignant transformation. In this issue, Krizhanovsky et al. (2008) report that senescence is an important player not only in tumor suppression but also in the response of liver tissue to injury.
Comment on
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Senescence of activated stellate cells limits liver fibrosis.Cell. 2008 Aug 22;134(4):657-67. doi: 10.1016/j.cell.2008.06.049. Cell. 2008. PMID: 18724938 Free PMC article.
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