Gle1 does double duty
- PMID: 18724928
- DOI: 10.1016/j.cell.2008.08.009
Gle1 does double duty
Abstract
During nuclear export, Gle1 (the nuclear-pore-associated mRNA export factor) activates the DEAD-box protein Dbp5 to remodel exported mRNA-protein complexes on the cytoplasmic face of the nuclear pore complex. In this issue, Bolger et al. (2008) now report additional roles for Gle1 in translation initiation and termination.
Comment on
-
The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation.Cell. 2008 Aug 22;134(4):624-33. doi: 10.1016/j.cell.2008.06.027. Cell. 2008. PMID: 18724935 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
